Quasi-Mendelian paternal inheritance of mitochondrial DNA: A notorious artifact, or anticipated behavior?
نویسندگان
چکیده
منابع مشابه
Mitochondrial DNA Mutations, Pathogenicity and Inheritance
Mitochondria contain their own DNA (mtDNA), which codes for 13 proteins (all subunits of the respiratory chain complexes), 22 tRNAs and 2 rRNAs. Several mtDNA point mutations as well as deletions have been shown to be causative in well-defined mitochondrial disorders. A mixture of mutated and wild type mtDNA (heteroplasmy) is found in most of these disorders. Inheritance of mtDNA is maternal, a...
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Mitochondrial DNA is the primary tool in the investigation of recent evolutionary history, particularly for uncovering human origins and expansion. Maternal inheritance of mitochondria enables models of population history to be much simpler that those needed for the analysis of nuclear DNA. The recent report of a man with his father’s mitochondria suggests a rethink of mitochondrial evolutionar...
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The new millennium is characterized by speed and distribution in every aspect of most business and organization undertaking. Organizations are challenged to bring ideas and concepts to products and services in an ever-increasing pace. Companies distributed by space, time and capabilities come together to deliver products and solutions for which there is any need in the global marketplace. This ...
متن کاملNon-Mendelian inheritance of DNA-induced inositol independence in Neurospora.
Inositol-independent (inos(+)) revertants of Neurospora induced in inositol-requiring mutants by treatment with wild-type DNA in previous studies were found to be stable and to grow well in the absence of inositol. Genetic data presented in this paper show that a major proportion of these induced revertants rarely transmitted the inositol independence character (inos(+)) to their sexual progeny...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2019
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1821436116